COP1 Antibody - N-terminal region
Produktgrößen
400ul
£597,00
OAAB07574-400UL
Über dieses Produkt
- SKU:
- OAAB07574
- Zusätzliche Namen:
- COP; COP1; PSEUDO-ICE; LLID-114769
- Klonalität:
- Polyclonal
- Konzentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Weitere Details:
- Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death; TNF-alpha; hypoxia-; UV-; and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4; possibly by preventing the interaction between CASP1 and RIPK2.
- Host:
- Rabbit
- Immunogen:
- This COP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human COP1.
- Isotyp:
- Ig
- Molekulargewicht:
- 23 kDa
- Proteindetails:
- Caspase recruitment domain-containing protein 16
- Aufreinigung:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php