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Antikörper

BAX Antibody

Produktgrößen
400ul
£615,00
OAAB07085-400UL
Über dieses Produkt
SKU:
OAAB07085
Zusätzliche Namen:
BCL2L4
translate.label.attr.clone:
557CT5.2.1
Klonalität:
Monoclonal
Konzentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Weitere Details:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2; and functions as an apoptotic activator. This protein is reported to interact with; and increase the opening of; the mitochondrial voltage-dependent anion channel (VDAC); which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants; which encode different isoforms; have been reported for this gene.
Host:
Mouse
Immunogen:
This BAX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from human BAX .
Isotyp:
IgG2b
Molekulargewicht:
21184 Da
Proteindetails:
Apoptosis regulator BAX
Aufreinigung:
This antibody is purified through a protein G column; followed by dialysis against PBS.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody