CYP27B1 Antibody - C-terminal region
Produktgrößen
200ul
£615,00
OAAB05644-200UL
Über dieses Produkt
- SKU:
- OAAB05644
- Zusätzliche Namen:
- VDR; CP2B; CYP1; PDDR; VDD1; VDDR; VDDRI; CYP27B; P450c1; CYP1alpha
- Klonalität:
- Polyclonal
- Konzentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Weitere Details:
- CYP27B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha;25-dihydroxyvitamin D3; the active form of vitamin D3; which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.
- Host:
- Rabbit
- Immunogen:
- This CYP27B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-508 amino acids from the C-terminal region of human CYP27B1.
- Isotyp:
- Rabbit Ig
- Molekulargewicht:
- 56504 Da
- Proteindetails:
- 25-hydroxyvitamin D-1 alpha hydroxylase; mitochondrial
- Aufreinigung:
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php