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Antikörper

ANTXR1 Antibody

Produktgrößen
400ul
£597,00
OAAB04785-400UL
Über dieses Produkt
SKU:
OAAB04785
Zusätzliche Namen:
ATR; GAPO; TEM8
Klonalität:
Polyclonal
Konzentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Weitere Details:
ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin; the causative agent of the disease; anthrax. The binding of the protective antigen (PA) component; of the tripartite anthrax toxin; to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell; the other two components of anthrax toxin; edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Host:
Rabbit
Immunogen:
This ANTXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from human ANTXR1.
Isotyp:
Rabbit Ig
Molekulargewicht:
63 kDa
Proteindetails:
Anthrax toxin receptor 1
Aufreinigung:
This antibody is purified through a protein A column; followed by peptide affinity purification.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody