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Antikörper

DDR2 Antibody

Produktgrößen
400ul
£597,00
OAAB04761-400UL
Über dieses Produkt
SKU:
OAAB04761
Zusätzliche Namen:
TKT; WRCN; MIG20a; NTRKR3; TYRO10
Klonalität:
Polyclonal
Konzentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Weitere Details:
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth; differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules; which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular; transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain; not previously described for RTKs.
Host:
Rabbit
Immunogen:
This TYRO10 antibody is generated from rabbits immunized with a his tag recombinant protein of human TYRO10.
Isotyp:
Ig
Molekulargewicht:
96736 Da
Proteindetails:
Discoidin domain-containing receptor 2
Aufreinigung:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody