CDH1 Antibody - N-terminal region
Produktgrößen
400ul
£615,00
OAAB01229-400UL
Über dieses Produkt
- SKU:
- OAAB01229
- Zusätzliche Namen:
- UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
- Klonalität:
- Polyclonal
- Konzentration:
- 2 mg/ml
- Weitere Details:
- CDH1 is a classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. Mutations are correlated with gastric; breast; colorectal; thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation; invasion; and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization.
- Host:
- Rabbit
- Immunogen:
- This E Cadherin (CDH1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-189 amino acids from the N-terminal region of human E Cadherin (CDH1).
- Isotyp:
- Rabbit Ig
- Molekulargewicht:
- 97 kDa
- Proteindetails:
- Cadherin-1
- Aufreinigung:
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php