CASP5 Antibody - middle region
Produktgrößen
400ul
£597,00
OAAB00965-400UL
Über dieses Produkt
- SKU:
- OAAB00965
- Zusätzliche Namen:
- ICH-3; ICEREL-III; ICE(rel)III
- Klonalität:
- Polyclonal
- Konzentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Weitere Details:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max; a central component of the Myc/Max/Mad transcription regulation network important for cell growth; differentiation; and apoptosis; is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
- Host:
- Rabbit
- Immunogen:
- This CASP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human CASP5.
- Isotyp:
- Rabbit Ig
- Molekulargewicht:
- 50 kDa
- Proteindetails:
- Caspase-5
- Aufreinigung:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php