CHRNB3 antibody - middle region
Produktgrößen
25ul
£177,00
AVARP13021-P050-25UL
100 ul
£412,00
AVARP13021-P050-100UL
Über dieses Produkt
- SKU:
- AVARP13021-P050
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described; alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand; the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia; Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction.
- Gendetails:
- Cholinergic receptor; nicotinic; beta 3 (neuronal)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human CHRNB3
- Molekulargewicht:
- 53kDa
- Proteindetails:
- Neuronal acetylcholine receptor subunit beta-3
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php