CDKN2B antibody - middle region
Produktgrößen
25ul
£177,00
AVARP03047-P050-25UL
100 ul
£412,00
AVARP03047-P050-100UL
Über dieses Produkt
- SKU:
- AVARP03047-P050
- Zusätzliche Namen:
- P15; MTS2; TP15; CDK4I; INK4B; p15INK4b
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor; which forms a complex with CDK4 or CDK6; and prevents the activation of the CDK kinases; thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta; which suggested its role in the TGF beta induced growth inhibition.
- Gendetails:
- Cyclin-dependent kinase inhibitor 2B (p15; inhibits CDK4)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human CDKN2B
- Molekulargewicht:
- 15kDa
- Proteindetails:
- Cyclin-dependent kinase 4 inhibitor B
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php