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Antikörper

CDKN1B antibody - C-terminal region

Produktgrößen
25ul
£177,00
AVARP03039-P050-25UL
100 ul
£412,00
AVARP03039-P050-100UL
Über dieses Produkt
SKU:
AVARP03039-P050
Zusätzliche Namen:
KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
CDKN1B is a cyclin-dependent kinase inhibitor; which shares a limited similarity with CDK inhibitor CDKN1A/p21. It binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes; and thus controls the cell cycle progression at G1. The degradation of this protein; which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes; is required for the cellular transition from quiescence to the proliferative state.This gene encodes a cyclin-dependent kinase inhibitor; which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes; and thus controls the cell cycle progression at G1. The degradation of this protein; which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes; is required for the cellular transition from quiescence to the proliferative state. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gendetails:
Cyclin-dependent kinase inhibitor 1B (p27; Kip1)
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human CDKN1B
Molekulargewicht:
22kDa
Proteindetails:
Cyclin-dependent kinase inhibitor 1B
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody