CDC42 antibody - N-terminal region
Produktgrößen
25ul
£177,00
AVARP01017-P050-25UL
100 ul
£412,00
AVARP01017-P050-100UL
Über dieses Produkt
- SKU:
- AVARP01017-P050
- Zusätzliche Namen:
- TKS; G25K; CDC42Hs
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CDC42 is a small GTPase of the Rho-subfamily; which regulates signaling pathways that control diverse cellular functions including cell morphology; migration; endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42; and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP); which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.The protein encoded by this gene is a small GTPase of the Rho-subfamily; which regulates signaling pathways that control diverse cellular functions including cell morphology; migration; endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42; and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP); which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
- Gendetails:
- Cell division cycle 42 (GTP binding protein; 25kDa)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human CDC42
- Molekulargewicht:
- 21kDa
- Proteindetails:
- Cell division control protein 42 homolog
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php