GTF2H1 Antibody Middle region
Produktgrößen
25ul
£177,00
ARP97725-P050-25UL
100 ul
£412,00
ARP97725-P050-100UL
Über dieses Produkt
- SKU:
- ARP97725-P050
- Zusätzliche Namen:
- P62; BTF2; TFB1; TFIIH
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Component of the general transcription and DNA repair factor IIH (TFIIH) core complex; which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and; when complexed to CAK; in RNA transcription by RNA polymerase II. In NER; TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription; TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established; TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
- Gendetails:
- general transcription factor IIH subunit 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human GTF2H1
- Molekulargewicht:
- 60 kDa
- Proteindetails:
- P62; BTF2; TFB1; TFIIH
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php