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Antikörper

Anti-CDC27

Produktgrößen
25ul
£177,00
ARP96752-P050-25UL
100 ul
£412,00
ARP96752-P050-100UL
Über dieses Produkt
SKU:
ARP96752-P050
Zusätzliche Namen:
APC3; HNUC; NUC2; H-NUC; ANAPC3; CDC27Hs; D0S1430E; D17S978E
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27; and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC); which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate; which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats; which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2; p55CDC and BUBR1; and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2; 22 and Y.
Gendetails:
cell division cycle 27
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human CDC27
Molekulargewicht:
90 kDa
Proteindetails:
cell division cycle protein 27 homolog
Aufreinigung:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody