Anti-Olfm2
Produktgrößen
25ul
£177,00
ARP93771-P050-25UL
100 ul
£412,00
ARP93771-P050-100UL
Über dieses Produkt
- SKU:
- ARP93771-P050
- Zusätzliche Namen:
- A030009A06Rik
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation (By similarity). TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF; causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes (By similarity). Plays a role in AMPAR complex organization. Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching; that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling (By similarity).
- Gendetails:
- olfactomedin 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of mouse OLFM2
- Molekulargewicht:
- 51 kDa
- Proteindetails:
- noelin-2
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php