FXYD2 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP91335-P050-25UL
100 ul
£412,00
ARP91335-P050-100UL
Über dieses Produkt
- SKU:
- ARP91335-P050
- Zusätzliche Namen:
- Atp1; Atp1g1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain; beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2; also known as the gamma subunit of the Na;K-ATPase; regulates the properties of that enzyme. FXYD1 (phospholemman); FXYD2 (gamma); FXYD3 (MAT-8); FXYD4 (CHIF); and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2); with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The Type III integral membrane protein encoded by this gene is the gamma subunit of the Na;K-ATPase present on the plasma membrane. Although the Na;K-ATPase does not depend on the gamma subunit to be functional; it is thought that the gamma subunit modulates the enzyme's activity by inducing ion channel activity. Multiple transcript variants have been described for this gene that are expressed in tissue-specific and developmental stage-specific patterns and encode proteins that differ at the N-terminus.
- Gendetails:
- FXYD domain-containing ion transport regulator 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle terminal region of Mouse FXYD2
- Molekulargewicht:
- 7 kDa
- Proteindetails:
- Sodium/potassium-transporting ATPase subunit gamma
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php