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Antikörper

Arg2 Antibody Middle region

Produktgrößen
25ul
£177,00
ARP89524-P050-25UL
100 ul
£412,00
ARP89524-P050-100UL
Über dieses Produkt
SKU:
ARP89524-P050
Zusätzliche Namen:
AII; AU022422
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4+ and CD8+ T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May contribute to the immune evasion of H.pylori by restricting M1 macrophage activation and polyamine metabolism. May play a role in promoting prenatal immune suppression (By similarity). Regulates RPS6KB1 signaling; which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction. Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling. Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity (By similarity).
Gendetails:
arginase type II
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of mouse ARG2
Molekulargewicht:
38 kDa
Proteindetails:
arginase-2; mitochondrial
Aufreinigung:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody