Gdnf Antibody
Produktgrößen
25ul
£177,00
ARP88898-P050-25UL
100 ul
£412,00
ARP88898-P050-100UL
Über dieses Produkt
- SKU:
- ARP88898-P050
- Zusätzliche Namen:
- ATF; AI385739
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein; a highly conserved neurotrophic factor; was shown to promote the survival and differentiation of dopaminergic neurons in culture; and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Homozygous knockout mice for this gene exhibit defects in kidney development and neonatal death. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing.
- Gendetails:
- glial cell line derived neurotrophic factor
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle terminal region of mouse GDNF
- Molekulargewicht:
- 23 kDa
- Proteindetails:
- Glial cell line-derived neurotrophic factor
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php