BCL10 Antibody
Produktgrößen
25ul
£177,00
ARP88067-P050-25UL
100 ul
£412,00
ARP88067-P050-100UL
Über dieses Produkt
- SKU:
- ARP88067-P050
- Zusätzliche Namen:
- CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD); and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9; 10; 11 and 14; which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1; a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB; and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
- Gendetails:
- B-cell CLL/lymphoma 10
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle terminal region of human BCL10
- Molekulargewicht:
- 25 kDa
- Proteindetails:
- B-cell lymphoma/leukemia 10
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php