DDB2 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP87433-P050-25UL
100 ul
£412,00
ARP87433-P050-100UL
Über dieses Produkt
- SKU:
- ARP87433-P050
- Zusätzliche Namen:
- XPE; DDBB; UV-DDB2
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair; and this complex mediates the ubiquitylation of histones H3 and H4; which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E; a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development; in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- damage-specific DNA binding protein 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human DDB2
- Molekulargewicht:
- 46 kDa
- Proteindetails:
- DNA damage-binding protein 2
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php