CASP12 Antibody
Produktgrößen
25ul
£177,00
ARP87181-P050-25UL
100 ul
£412,00
ARP87181-P050-100UL
Über dieses Produkt
- SKU:
- ARP87181-P050
- Zusätzliche Namen:
- CASP-12; CASP12P1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents; the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However; in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.
- Gendetails:
- caspase 12 (gene/pseudogene)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human CASP12
- Molekulargewicht:
- 28 kDa
- Proteindetails:
- Inactive caspase-12
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php