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Antikörper

FGFR2 Antibody - middle region

Produktgrößen
25ul
£177,00
ARP86818-P050-25UL
100 ul
£412,00
ARP86818-P050-100UL
Über dieses Produkt
SKU:
ARP86818-P050
Zusätzliche Namen:
BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
The protein encoded by this gene is a member of the fibroblast growth factor receptor family; where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic; basic and/or keratinocyte growth factor; depending on the isoform. Mutations in this gene are associated with Crouzon syndrome; Pfeiffer syndrome; Craniosynostosis; Apert syndrome; Jackson-Weiss syndrome; Beare-Stevenson cutis gyrata syndrome; Saethre-Chotzen syndrome; and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gendetails:
fibroblast growth factor receptor 2
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human FGFR2
Molekulargewicht:
77 kDa
Proteindetails:
Fibroblast growth factor receptor 2
Aufreinigung:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody