E2F4 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP86817-P050-25UL
100 ul
£412,00
ARP86817-P050-100UL
Über dieses Produkt
- SKU:
- ARP86817-P050
- Zusätzliche Namen:
- E2F-4
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain; a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP); a transactivation domain enriched in acidic amino acids; and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB; p107 and p130; but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes; and its gene mutation and increased expression may be associated with human cancer.
- Gendetails:
- E2F transcription factor 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of Human E2F4
- Molekulargewicht:
- 45 kDa
- Proteindetails:
- Transcription factor E2F4
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php