GIT2 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP84867-P050-25UL
100 ul
£412,00
ARP84867-P050-100UL
Über dieses Produkt
- SKU:
- ARP84867-P050
- Zusätzliche Namen:
- PKL; CAT2; CAT-2
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a member of the GIT protein family; which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes; focal adhesions; and the cell periphery; and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover; and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms; but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences; with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.
- Gendetails:
- G protein-coupled receptor kinase interacting ArfGAP 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human GIT2
- Molekulargewicht:
- 83 kDa
- Proteindetails:
- ARF GTPase-activating protein GIT2
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php