BRCC3 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP81799-P050-25UL
100 ul
£412,00
ARP81799-P050-100UL
Über dieses Produkt
- SKU:
- ARP81799-P050
- Zusätzliche Namen:
- C6.1A; BRCC36; CXorf53
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC); which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response; where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains; and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya; a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.
- Gendetails:
- BRCA1/BRCA2-containing complex subunit 3
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human BRCC3
- Molekulargewicht:
- 34 kDa
- Proteindetails:
- lys-63-specific deubiquitinase BRCC36
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php