DCLK1 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP81225-P050-25UL
100 ul
£412,00
ARP81225-P050-100UL
Über dieses Produkt
- SKU:
- ARP81225-P050
- Zusätzliche Namen:
- CL1; DCLK; CLICK1; DCDC3A; DCAMKL1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains; which bind microtubules and regulate microtubule polymerization; a C-terminal serine/threonine protein kinase domain; which shows substantial homology to Ca2+/calmodulin-dependent protein kinase; and a serine/proline-rich domain in between the doublecortin and the protein kinase domains; which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes; including neuronal migration; retrograde transport; neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported; but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms; which are differentially expressed and have different kinase activities.
- Gendetails:
- doublecortin like kinase 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human DCLK1
- Molekulargewicht:
- 47 kDa
- Proteindetails:
- serine/threonine-protein kinase DCLK1
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php