FGFR4 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP80744-P050-25UL
100 ul
£412,00
ARP80744-P050-100UL
Über dieses Produkt
- SKU:
- ARP80744-P050
- Zusätzliche Namen:
- TKF; JTK2; CD334
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family; where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. The genomic organization of this gene; compared to members 1-3; encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed; there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms; as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and; although its specific function is unknown; it is overexpressed in gynecological tumor samples; suggesting a role in breast and ovarian tumorigenesis.
- Gendetails:
- fibroblast growth factor receptor 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human FGFR4
- Molekulargewicht:
- 83 kDa
- Proteindetails:
- fibroblast growth factor receptor 4
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php