ABL1 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP80033-P050-25UL
100 ul
£412,00
ARP80033-P050-100UL
Über dieses Produkt
- SKU:
- ARP80033-P050
- Zusätzliche Namen:
- ABL; JTK7; p150; c-ABL; v-abl; CHDSKM; c-ABL1; BCR-ABL; bcr/abl
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes; including cell division; adhesion; differentiation; and response to stress. The activity of the protein is negatively regulated by its SH3 domain; whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation; suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias; most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants; which contain alternative first exons that are spliced to the remaining common exons.
- Gendetails:
- ABL proto-oncogene 1; non-receptor tyrosine kinase
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human ABL1
- Molekulargewicht:
- 124 kDa
- Proteindetails:
- tyrosine-protein kinase ABL1
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php