EPB49 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP79851-P050-25UL
100 ul
£412,00
ARP79851-P050-100UL
Über dieses Produkt
- SKU:
- ARP79851-P050
- Zusätzliche Namen:
- DMT; EPB49
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes; by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus; and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes; this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region; where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease; while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Gendetails:
- dematin actin binding protein
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human EPB49
- Molekulargewicht:
- 40 kDa
- Proteindetails:
- dematin
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php