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Antikörper

FGFR3 Antibody - C-terminal region

Produktgrößen
25ul
£177,00
ARP79659-P050-25UL
100 ul
£412,00
ARP79659-P050-100UL
Über dieses Produkt
SKU:
ARP79659-P050
Zusätzliche Namen:
ACH; CEK2; JTK4; CD333; HSFGFR3EX
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family; with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Gendetails:
fibroblast growth factor receptor 3
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human FGFR3
Molekulargewicht:
52 kDa
Proteindetails:
fibroblast growth factor receptor 3
Aufreinigung:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody