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Antikörper

ERBB4 Antibody - C-terminal region

Produktgrößen
25ul
£177,00
ARP78920-P050-25UL
100 ul
£412,00
ARP78920-P050-100UL
Über dieses Produkt
SKU:
ARP78920-P050
Zusätzliche Namen:
HER4; ALS19; p180erbB4
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains; a transmembrane domain; a tyrosine kinase domain; a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however; not all variants have been fully characterized.
Gendetails:
erb-b2 receptor tyrosine kinase 4
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human ERBB4
Molekulargewicht:
52 kDa
Proteindetails:
receptor tyrosine-protein kinase erbB-4
Aufreinigung:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody