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Antikörper

DSC3 Antibody - middle region

Produktgrößen
25ul
£177,00
ARP76097-P050-25UL
100 ul
£412,00
ARP76097-P050-100UL
Über dieses Produkt
SKU:
ARP76097-P050
Zusätzliche Namen:
DSC; DSC1; DSC2; DSC4; CDHF3; HT-CP
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members; along with the desmogleins; are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18; occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases; and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.
Gendetails:
desmocollin 3
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human DSC3
Molekulargewicht:
92 kDa
Proteindetails:
desmocollin-3
Aufreinigung:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody