DMP1 Antibody - N-terminal
Produktgrößen
25ul
£177,00
ARP74929-P050-25UL
100 ul
£412,00
ARP74929-P050-100UL
Über dieses Produkt
- SKU:
- ARP74929-P050
- Zusätzliche Namen:
- ARHP; ARHR; DMP-1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein; which is critical for proper mineralization of bone and dentin; is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains; multiple phosphorylation sites; a functional arg-gly-asp cell attachment sequence; and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix; where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia; a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human DMP1
- Molekulargewicht:
- 54 kDa
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php