GAD1 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP74535-P050-25UL
100 ul
£412,00
ARP74535-P050-100UL
Über dieses Produkt
- SKU:
- ARP74535-P050
- Zusätzliche Namen:
- GAD; SCP; CPSQ1; DEE89
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes one of several forms of glutamic acid decarboxylase; identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products; the predominant 67-kD form and a less-frequent 25-kD form.
- Gendetails:
- glutamate decarboxylase 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human GAD1
- Molekulargewicht:
- 65 kDa
- Proteindetails:
- glutamate decarboxylase 1
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php