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Antikörper

CBX7 Antibody - C-terminal region

Produktgrößen
25ul
£177,00
ARP74429-P050-25UL
100 ul
£412,00
ARP74429-P050-100UL
Über dieses Produkt
SKU:
ARP74429-P050
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex; a complex class required to maintain the transcriptionally repressive state of many genes; including Hox genes; throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119'; rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones; and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A; but not by inducing telomerase activity.
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human CBX7
Molekulargewicht:
27 kDa
Aufreinigung:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody