CAND1 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP74426-P050-25UL
100 ul
£412,00
ARP74426-P050-100UL
Über dieses Produkt
- SKU:
- ARP74426-P050
- Zusätzliche Namen:
- TIP120; TIP120A
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes; thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation: in the deneddylated state; cullin-binding CAND1 binds CUL1-RBX1; increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes.
- Gendetails:
- cullin-associated and neddylation-dissociated 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human CAND1
- Molekulargewicht:
- 118 kDa
- Proteindetails:
- cullin-associated NEDD8-dissociated protein 1
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php