FAK2 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP74156-P050-25UL
100 ul
£412,00
ARP74156-P050-100UL
Über dieses Produkt
- SKU:
- ARP74156-P050
- Zusätzliche Namen:
- PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration; nicotinic acetylcholine receptor activation; membrane depolarization; or protein kinase C activation. This protein has been shown to bind CRK-associated substrate; nephrocystin; GTPase regulator associated with FAK; and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.
- Gendetails:
- protein tyrosine kinase 2 beta
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of Human FAK2
- Molekulargewicht:
- 106kDa
- Proteindetails:
- protein-tyrosine kinase 2-beta
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php