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Antikörper

APLP2 Antibody - middle region

Produktgrößen
25ul
£177,00
ARP73748-P050-25UL
100 ul
£412,00
ARP73748-P050-100UL
Über dieses Produkt
SKU:
ARP73748-P050
Zusätzliche Namen:
APPH; APPL2; CDEBP; APLP-2
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
This gene encodes amyloid precursor- like protein 2 (APLP2); which is a member of the APP (amyloid precursor protein) family including APP; APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-; copper- and zinc- binding domains at the N-terminus; BPTI/Kunitz inhibitor and E2 domains in the middle region; and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission; spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human APLP2
Molekulargewicht:
83kDa
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody