FANCD2 Antibody - middle region
Produktgrößen
25ul
£177,00
ARP72576-P050-25UL
100 ul
£412,00
ARP72576-P050-100UL
Über dieses Produkt
- SKU:
- ARP72576-P050
- Zusätzliche Namen:
- FA4; FAD; FACD; FAD2; FA-D2; FANCD
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- The Fanconi anemia complementation group (FANC) currently includes FANCA; FANCB; FANCC; FANCD1 (also called BRCA2); FANCD2; FANCE; FANCF; FANCG; FANCI; FANCJ (also called BRIP1); FANCL; FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability; hypersensitivity to DNA crosslinking agents; increased chromosomal breakage; and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage; resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.
- Gendetails:
- Fanconi anemia complementation group D2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human FANCD2
- Molekulargewicht:
- 82kDa
- Proteindetails:
- Fanconi anemia group D2 protein
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php