EIF5A Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP70188-P050-25UL
100 ul
£412,00
ARP70188-P050-100UL
Über dieses Produkt
- SKU:
- ARP70188-P050
- Zusätzliche Namen:
- EIF-5A; EIF5A1; eIF-4D; eIF5AI
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- EIF5A is a mRNA-binding protein involved in translation elongation. It has an important function at the level of mRNA turnover; probably acting downstream of decapping. It is involved in actin dynamics and cell cycle progression; mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP; EIF5A functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. EIF5A regulates also TNF-alpha-mediated apoptosis and mediates effects of polyamines on neuronal process extension and survival. It may play an important role in brain development and function; and in skeletal muscle stem cell differentiation. EIF5A is also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein; essential for mRNA export of retroviral transcripts.
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human EIF5A
- Molekulargewicht:
- 20kDa
- Proteindetails:
- Eukaryotic translation initiation factor 5A-1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php