CKMT1B Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP67458-P050-25UL
100 ul
£412,00
ARP67458-P050-100UL
Über dieses Produkt
- SKU:
- ARP67458-P050
- Zusätzliche Namen:
- CKMT; CKMT1; UMTCK
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier; creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes; sarcomeric MtCK and ubiquitous MtCK; encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers; in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CKMT1B
- Molekulargewicht:
- 45kDa
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php