Chmp5 Antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP65870-P050-25UL
100 ul
£412,00
ARP65870-P050-100UL
Über dieses Produkt
- SKU:
- ARP65870-P050
- Zusätzliche Namen:
- AW545668; 2210412K09Rik
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Chmp5 is a probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins; such as stimulated growth factor receptors; lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O; -I;-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events; such as the terminal stages of cytokinesis. ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities; possibly in conjunction with the AAA ATPase VPS4.
- Gendetails:
- charged multivesicular body protein 5
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Chmp5
- Molekulargewicht:
- 24kDa
- Proteindetails:
- Charged multivesicular body protein 5
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php