CYFIP1 Antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP64537-P050-25UL
100 ul
£412,00
ARP64537-P050-100UL
Über dieses Produkt
- SKU:
- ARP64537-P050
- Zusätzliche Namen:
- SHYC; SRA1; SRA-1; P140SRA-1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers.
- Gendetails:
- Cytoplasmic FMR1 interacting protein 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYFIP1
- Molekulargewicht:
- 145kDa
- Proteindetails:
- Cytoplasmic FMR1-interacting protein 1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php