CD33 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP63067-P050-25UL
100 ul
£412,00
ARP63067-P050-100UL
Über dieses Produkt
- SKU:
- ARP63067-P050
- Zusätzliche Namen:
- p67; SIGLEC3; SIGLEC-3
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response; CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro).
- Gendetails:
- CD33 molecule
- Host:
- Rabbit
- Molekulargewicht:
- 38kDa
- Proteindetails:
- Myeloid cell surface antigen CD33
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php