GALR2 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP61395-P050-25UL
100 ul
£412,00
ARP61395-P050-100UL
Über dieses Produkt
- SKU:
- ARP61395-P050
- Zusätzliche Namen:
- GAL2-R; GALNR2; GALR-2
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Galanin is an important neuromodulator present in the brain; gastrointestinal system; and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion; inhibits cardiac vagal slowing of heart rate; abolishes sinus arrhythmia; and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq); in contrast to GALR1; which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However; it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
- Gendetails:
- Galanin receptor 2
- Host:
- Rabbit
- Molekulargewicht:
- 43kDa
- Proteindetails:
- Galanin receptor type 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php