CCM2 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP60630-P050-25UL
100 ul
£412,00
ARP60630-P050-100UL
Über dieses Produkt
- SKU:
- ARP60630-P050
- Zusätzliche Namen:
- OSM; C7orf22; PP10187
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure; cell-cell interactions; and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- cerebral cavernous malformation 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CCM2
- Molekulargewicht:
- 51 kDa
- Proteindetails:
- Malcavernin
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php