CTSC antibody - middle region
Produktgrößen
25ul
£177,00
ARP60116-P050-25UL
100 ul
£412,00
ARP60116-P050-100UL
Über dieses Produkt
- SKU:
- ARP60116-P050
- Zusätzliche Namen:
- JP; HMS; JPD; PLS; CPPI; DPP1; DPPI; PALS; DPP-I; PDON1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CTSC is a member of the peptidase C1 family; is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains; both produced from a single protein precursor; and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome; an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
- Gendetails:
- Cathepsin C
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human CTSC
- Molekulargewicht:
- 8kDa
- Proteindetails:
- Dipeptidyl peptidase 1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php