F8 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP60040-P050-25UL
100 ul
£412,00
ARP60040-P050-100UL
Über dieses Produkt
- SKU:
- ARP60040-P050
- Zusätzliche Namen:
- AHF; F8B; F8C; HEMA; FVIII; DXS1253E
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes coagulation factor VIII; which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which; in the presence of Ca+2 and phospholipids; converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein; isoform a; which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein; isoform b; which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A; a common recessive X-linked coagulation disorder.
- Gendetails:
- Coagulation factor VIII; procoagulant component
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human F8
- Molekulargewicht:
- 79kDa
- Proteindetails:
- Coagulation factor VIII
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php