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Antikörper

CNTFR antibody - C-terminal region

Produktgrößen
25ul
£177,00
ARP59996-P050-25UL
100 ul
£412,00
ARP59996-P050-100UL
Über dieses Produkt
SKU:
ARP59996-P050
Zusätzliche Namen:
MGC1774
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex; which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component; which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression; cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants; both encoding the same protein; have been identified.
Gendetails:
Ciliary neurotrophic factor receptor
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human CNTFR
Molekulargewicht:
41 kDa
Proteindetails:
Ciliary neurotrophic factor receptor subunit alpha
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody