Arhgef4 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP59254-P050-25UL
100 ul
£412,00
ARP59254-P050-100UL
Über dieses Produkt
- SKU:
- ARP59254-P050
- Zusätzliche Namen:
- As; Asef; 9330140K16Rik; C230030N03Rik
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Arhgef4 acts as guanine nucleotide exchange factor (GEF) for RHOA; RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion By similarity. It is required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Arhgef4 is involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
- Gendetails:
- Rho guanine nucleotide exchange factor (GEF) 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Arhgef4
- Molekulargewicht:
- 57kDa
- Proteindetails:
- Rho guanine nucleotide exchange factor 4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php