CASP5 antibody - middle region
Produktgrößen
25ul
£177,00
ARP58992-P050-25UL
100 ul
£412,00
ARP58992-P050-100UL
Über dieses Produkt
- SKU:
- ARP58992-P050
- Zusätzliche Namen:
- ICH-3; ICEREL-III; ICE(rel)III
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max; a central component of the Myc/Max/Mad transcription regulation network important for cell growth; differentiation; and apoptosis; is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
- Gendetails:
- Caspase 5; apoptosis-related cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human CASP5
- Molekulargewicht:
- 43kDa
- Proteindetails:
- Caspase-5
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php